Afalino is indicated for treating partial-onset seizures in adult patients.
Medication should be taken according to the advice of a registered healthcare provider.
🛒 How to order this item?
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Show More
Cenobamate
Anti-epileptic drugs
The inhibition of voltage-gated sodium channels increases the threshold for generating action potentials and decreases the number of action potentials.1
Cenobamate functions as a positive modulator of the GABA-A receptor and inhibits voltage-gated sodium channels. This inhibition raises the threshold for action potential generation, thereby reducing the frequency of action potentials. The combination of these two mechanisms may enhance its effectiveness in controlling seizures.
In the case of an overdose, Afalino should be discontinued, and general supportive care should be provided until the clinical toxicity subsides or resolves.
Cenobamate can be administered with or without food, or as directed by a physician. The recommended dosage for partial-onset seizures in adults is as follows:
Initial Dosage:
- Weeks 1 and 2: 12.5 mg once daily.
Titration Regimen:
- Weeks 3 and 4: 25 mg once daily.
- Weeks 5 and 6: 50 mg once daily.
- Weeks 7 and 8: 100 mg once daily.
- Weeks 9 and 10: 150 mg once daily.
Maintenance Dosage:
- From Week 11 onward: 200 mg once daily.
Maximum Dosage:
- If clinically necessary and well-tolerated, the dose may be increased beyond 200 mg in increments of 50 mg once daily every two weeks, up to a maximum of 400 mg once daily.
Medication should be taken according to the advice of a registered healthcare provider.
There are no sufficient studies on the use of Cenobamate in pregnant women, but it may pose risks to the fetus. It should be used during pregnancy only if the potential benefits outweigh the risks. There is no information available regarding the presence of Cenobamate in breast milk, its effects on breastfed infants, or its impact on milk production.
Store below 30 degrees Celsius, protected from light, and out of reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.